Endurance Case study · 1 twin pair

Identical twins, 30 years apart in training

At 52, the endurance-trained twin had a higher VO₂max, less body fat and more slow-twitch fibres, but less muscle size and strength than his untrained brother.

Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits

Bathgate KE, Bagley JR, Jo E, et al. · Eur J Appl Physiol · 2018

What they studied

Design
Case study
People
One pair of identical male twins, age 52
Contrast
More than 30 years of endurance training vs no regular exercise
Measures
Blood, heart and lung health, muscle size, strength, power, biopsies

What they found

  • The trained twin had a 12.4 ml/kg/min higher VO₂max and 8.6% lower body fat.
  • He also had lower resting heart rate, blood pressure, cholesterol, triglycerides and blood glucose.
  • His muscle had 55% more slow-twitch (type I) fibres and fewer fast-twitch IIa fibres.
  • But his muscle size and strength were lower, and muscle quality poorer, than his untrained brother’s.

How strong is the evidence

Case study · 1 twin pair

What this design cannot tell us:

  • One pair of twins: a vivid example, not proof that applies to everyone.
  • The twins also differed in other habits that were not controlled.

What it means for your training

  • Genes set the starting line, not the finish. Training reshaped heart, blood and muscle.
  • Endurance alone did not protect muscle size or strength. Pair it with strength work to keep both.

Our summary of the published abstract. Read the original paper for full details.

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